The NCQBCS

An NIH Biotechnology Research Resource

We are developing next-generation protein measurement technologies for a wide variety of biomedical applications. Our technologies are focused on making whole proteome analysis faster and broadly accessible. In addition to our technology development mission, we apply these technologies to various biomedical problems through collaboration. For those seeking to learn basic proteomic methodology or advanced training in our techniques, we offer hands-on learning experiences.

Director's Welcome

Thank you for visiting the NCQBCS. Our center was founded in 2016 through a grant from the…
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Team

Our team of researchers come from across the world and bring with them the know-how, passion, and drive.
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Funding

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News

Find out what’s happening at NCQBCS

March 9, 2017

Alexander Makarov visits NCQBCS

By haanen@wisc.edu
This week the NCQBCS hosted a visit from Alexander Makarov, Director of Research for Global Life Sciences Mass Spectrometry at Thermo Fisher…
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March 1, 2017

Predicting when blood goes bad

By haanen@wisc.edu
By John Arnst Despite the best efforts of blood banks and networks, some blood bags end up spoiling before they can make it to patients in n…
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July 22, 2016

New UW-Madison center offers ultra-speed protein analysis

By haanen@wisc.edu
By David Tenenbaum Three University of Wisconsin—Madison researchers have won a prestigious, five-year grant to establish the National Cente…
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July 12, 2016

UW-Madison Lands $6M NIH Grant for Mass Spec Development Center

By haanen@wisc.edu
A trio of scientists at the University of Wisconsin-Madison is launching a new research center to advance mass spectrometry-based proteomics…
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Science

Developing next-generation protein measurement technologies

 

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Technology

We develop reagents, methods, and instrumentation for faster proteome analysis. These technologies include multi-plexed chemical tags, NeuCode metabolic labels, sample preparation methods, and mass spectrometer modifications to allow quantitative whole proteome analysis in just minutes to hours.

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Biology

We have partnered with dozens of laboratories across the country with the aim to leveraging NCQBCS technologies to solve longstanding biological research questions. The goal for each of our collaborative projects is to produce at least one high-quality, high-impact publication.

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Collaboration

Our center is always seeking new collaborative opportunities in the fields of metabolism and biomedicine. If you think your work might benefit from NCQBCS technology please let us know. To help you get an idea of the scope and scale of current projects take a look at the descriptions of our current driving biomedical projects.

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Resources

Here we make our tools freely available

Reagents

If you would like to test any of our custom reagents please let us know. Presently we have a variety of NeuCode SILAC reagents and DiLeu chemical tags. We are always happy to help however we can.

Protocols and Tutorials

Over the years we’ve built up a whole library of protocols. Please browse our library, if you don’t see what you are looking for, just send us a note.

Software

Some of our technologies require custom software for data analysis.  In other cases the software is the technology. Here we make these tools freely available. We included our favorites from others as well.

Training

Keeping a mass spectrometer working can be challenging. Visit us for hands-on training that spans from an introduction to proteomics to advanced one-on-one interactions on a wide variety of topics.

Our overall aim is to promote, advertise, and make available our enabling technologies to the biomedical research community.

Check out our publications

Contact Us

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